• Adherence to Guidelines for Acute Rehabilitation in the Norwegian Trauma Plan. 

      Schäfer, Christoph; Moksnes, Håkon Øgreid; Rasmussen, Mari Storli; Hellstrøm, Torgeir; Søberg, Helene L.; Røise, Olav; Røe, Cecilie; K Frisvold, Shirin; Bartnes, Kristian; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; Brunborg, Cathrine; Andelic, Nada; Anke, Audny Gabriele Wagner (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-27)
      Objective: To evaluate adherence to 3 central operational recommendations for acute rehabilitation in the Norwegian trauma plan.<p> <p>Methods: A prospective multi-centre study of 538 adults with moderate and severe trauma with New Injury Severity Score >9. <p>Results: Adherence to the first recommendation, assessment by a physical medicine and rehabilitation physician within 72 h following ...
    • Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study 

      van Veen, Ernest; Van Der Jagt, Mathieu; Cnossen, Maryse C.; Maas, Andrew I. R.; De Beaufort, Inez D.; Menon, David K.; Citerio, Giuseppe; Stocchetti, Nino; Rietdijk, Wim J. R.; van Dijck, Jeroen T. J. M.; Kompanje, Erwin J. O.; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-16)
      <p><i>Background</i>: We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation.</p> <p><i>Methods</i>: Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study centers completed several questionnaires (response rate: 99%).</p> <p><i>Results</i>: Regarding practices around ...
    • Comparative effectiveness of intracranial hypertension management guided by ventricular versus intraparenchymal pressure monitoring: a CENTER-TBI study 

      Volovici, Victor; Pisică, Dana; Gravesteijn, Benjamin; Dirven, Clemens M. F.; Steyerberg, Ewout W.; Ercole, Ari; Stocchetti, Nino; Nelson, David; Menon, David K; Citerio, Giuseppe; Van Der Jagt, Mathieu; Maas, Andrew I. R.; Haitsma, Iain K.; Lingsma, Hester F.; Vik, Anne; Skandsen, Toril; Andelic, Nada; Røise, Olav; Helseth, Eirik; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-01)
      <b><p>Objective</b> To compare outcomes between patients with primary external ventricular device (EVD)–driven treatment of intracranial hypertension and those with primary intraparenchymal monitor (IP)–driven treatment. <b><p>Methods</b> The CENTER-TBI study is a prospective, multicenter, longitudinal observational cohort study that enrolled patients of all TBI severities from 62 participating ...
    • Description of health-related rehabilitation service provision and delivery in randomized controlled trials: A topic review 

      Andelic, Nada; Lu, Juan; Gutenbrunner, Christoph; Nugraha, Boya; Gormley, Mirinda; Søberg, Helene; Sveen, Unni; Anke, Audny; Kirkevold, Marit; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-18)
      Objective: To determine how health-related rehabilitation services have been described in recently pub-lished randomized clinical trials, using the International Classification System for Service Organization in Health-Related Rehabilitation (ICSO-R 2.0) as a framework.<p><p> Methods: Medline was searched for English--language randomized clinical trials (RCTs) published between 1 January 2018 and ...
    • Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury 

      Mikolic, Ana; van Klaveren, David; Oude Groeniger, Joost; Wiegers, E; Lingsma, Hester F; Zeldovich, Marina; von Steinbüchel, Nicole; Maas, Andrew I.R.; Roeters van Lennep, Jeanine; Polinder, Suzanne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-19)
      Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, treatment characteristics, and outcomes following mild and moderate/severe TBI. We performed mixed-effects regression analyses in the prospective multi-center Collaborative ...
    • Extended Coagulation Profiling in Isolated Traumatic Brain Injury: A CENTER-TBI Analysis 

      Böhm, Julia K.; Schaeben, Victoria; Schäfer, Nadine; Güting, Helge; Lefering, Rolf; Thorn, Sophie; Schöchl, Herbert; Zipperle, Johannes; Grottke, Oliver; Rolf, Rossaint; Stanworth, Simon; Curry, Nicola; Maegele, Marc; Åkerlund, Cecilia; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Vik, Anne; Anke, Audny Gabriele Wagner; Antoni, Anna; Audibert, Gérard; Azouvi, Philippe; Frisvold, Shirin; Skandsen, Toril; Helseth, Eirik; Røe, Cecilie; Røise, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-16)
      Background Trauma-induced coagulopathy in traumatic brain injury (TBI) remains associated with high rates of complications, unfavorable outcomes, and mortality. The underlying mechanisms are largely unknown. Embedded in the prospective multinational Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study, coagulation profiles beyond standard conventional ...
    • Factors associated with discharge destination from acute care after moderate-to-severe traumatic injuries in Norway: a prospective population-based study 

      Moksnes, Håkon Øgreid; Schäfer, Christoph; Rasmussen, Mari Storli; Søberg, Helene L.; Røise, Olav; Anke, Audny Gabriele Wagner; Røe, Cecilie; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; DAHL, HILDE MARGRETE; Hestnes, Morten; Brunborg, Cathrine; Andelic, Nada; Hellstrøm, Torgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-13)
      Background - Previous studies have demonstrated that the trauma population has needs for rehabilitation services that are best provided in a continuous and coordinated way. The discharge destination after acute care is the second step to ensuring quality of care. There is a lack of knowledge regarding the factors associated with the discharge destination for the overall trauma population. This paper ...
    • Family members’ experience with in-hospital health care after severe traumatic brain injury: a national multicentre study 

      Manskow, Unn Sollid; Arntzen, Cathrine; Damsgård, Elin; Braine, Mary; Sigurdardottir, Solrun; Andelic, Nada; Røe, Cecilie; Anke, Audny (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-07)
      <i>Background</i>: Family member’s experience and satisfaction of health care in the acute care and in-patient rehabilitation are important indicators of the quality of health care services provided to patients with severe traumatic brain injury (TBI). The objective was to assess family members’ experience of the health care provided in-hospital to patients with severe TBI, to relate experiences ...
    • The Family Needs Questionnaire-Revised: a Rasch analysis of measurement properties in the chronic phase after traumatic brain injury 

      Røe, Cecilie; Anke, Audny; Arango-Lasprilla, Juan Carlos; Andelic, Nada; Caracuel, Alfonso; Rivera, Diego Fernando; Norup, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-06)
      <p>Purpose - The main aim was to evaluate the measurement properties of the Family Needs Questionnaire-Revised (FNQ-R) in family members of individuals living with severe traumatic brain injury (TBI). <p>Methods - A total of 309 family members of individuals with severe TBI from Colombia, Denmark, Mexico, Norway and Spain participated. Rasch analysis of the FNQ-R and its 6 subscales was ...
    • Functional Outcomes at 6 and 12 Months Post-Injury in a Trauma Centre Population with Moderate-to-Severe Traumatic Injuries 

      Moksnes, Håkon Øgreid; Schafer, C.; Rasmussen, Mari Storli; Søberg, Helene L.; Røise, Olav; Anke, Audny Gabriele Wagner; Røe, Cecilie; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; Hestnes, Morten; Brunborg, Cathrine; Andelic, Nada; Hellstrøm, Torgeir; Dahl, Hilde Margrete (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-15)
      This study aims to evaluate the global functional outcomes after moderate-to-severe traumatic injury at 6 and 12 months and to examine the sociodemographic and injury-related factors that predict these outcomes. A prospective cohort study was conducted in which trauma patients of all ages with a New Injury Severity Score > 9 who were discharged alive from two regional trauma centres in Norway ...
    • Global Characterisation of Coagulopathy in Isolated Traumatic Brain Injury (iTBI): A CENTER-TBI Analysis 

      Böhm, JK; Güting, Helge; Thorn, S; Schäfer, Nadine; Rambach, V; Schöchl, Herbert; Grottke, Oliver; Rossaint, Rolf; Stanworth, Simon; Curry, Nicola; Lefering, Rolf; Maegele, Marc; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-11)
      <i>Background</i> - Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is associated with high rates of complications, unfavourable outcomes and mortality. The mechanism of the development of TBI-associated coagulopathy is poorly understood.<br><br> <i>Methods</i> - This analysis, embedded in the prospective, multi-centred, observational Collaborative European NeuroTrauma ...
    • Health-related Quality of Life 12 months after severe traumatic brain injury: A prospective nationwide cohort study 

      Søberg, Helene L.; Røe, Cecilie; Anke, Audny; Arango-Lasprilla, Juan Carlos; Skandsen, Toril; Sveen, Unni; von Steinbuchel, Nicole; Andelic, Nada (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      OBJECTIVE: To assess health-related quality of life in individuals with severe traumatic brain injury at 12 months post-injury, applying the Quality of Life after Brain Injury (QOLIBRI) instrument, and to study the relationship between injury-related factors, post-injury functioning and health-related quality of life. Design/subjects: The study is part of a prospective, Norwegian multicentre study ...
    • Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury 

      Gravesteijn, BY; Nieboer, Daan; Ercole, Ari; Lingsma, Hester F; Nelson, David; Van Calster, Ben; Steyerberg, Ewout W; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-19)
      <i>Objective</i> - We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury.<br><br> <i>Study Design and Setting</i> - We performed logistic regression (LR), lasso regression, and ridge regression with key baseline predictors in the IMPACT-II database (15 studies, <i>n</i> = 11,022). ML algorithms ...
    • Neuropsychological functioning in a national cohort of severe traumatic brain injury: demographic and acute injury-related predictors 

      Sigurdardottir, Solrun; Andelic, Nada; Wehling, Eike; Røe, Cecilie; Anke, Audny; Skandsen, Toril; Holthe, Øyvor; Jerstad, Tone; Aslaksen, Per Matti; Schanke, Anne-Kristine (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      Objectives: To determine the rates of cognitive impairment 1 year after severe traumatic brain injury (TBI) and to examine the influence of demographic, injury severity, rehabilitation, and subacute functional outcomes on cognitive outcomes 1 year after severe TBI.<p> Setting: National multicenter cohort study over 2 years.<p> Participants: Patients (N = 105), aged 16 years or older, with ...
    • Post-Concussion Symptoms in Complicated vs. Uncomplicated Mild Traumatic Brain Injury Patients at Three and Six Months Post-Injury: Results from the CENTER-TBI Study 

      Voomolen, DC; Haagsma, JA; Polinder, Suzanne; Maas, AIR; Steyerberg, Ewout W; Vulekovic, Peter; Sewalt, CA; Gravesteijn, BY; Covic, Amra; Andelic, Nada; Plass, AM; von Steinbüchel, Nicole; Vik, Anne; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin Kordasti; Helseth, Eirik; Skandsen, Toril; Røise, Olav; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-08)
      Abstract The aim of this study was to assess the occurrence of post-concussion symptoms and post-concussion syndrome (PCS) in a large cohort of patients after complicated and uncomplicated mild traumatic brain injury (mTBI) at three and six months post-injury. Patients were included through the prospective cohort study: Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI). Patients ...
    • Severe traumatic brain injury in Norway: Impact of age on outcome 

      Røe, Cecilie; Skandsen, Toril; Anke, Audny; Ader, Tiina; Vik, Anne; Lund, Stine Borgen; Manskow, Unn Sollid; Sollid, Snorre; Sundstrøm, Terje; Hestnes, Morten; Andelic, Nada (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      <i>Objective</i>: The aim of this study was to investigate the influence of age on mortality and 3-month outcome in a Norwegian cohort of patients with severe traumatic brain injury (TBI).<p> <p><i>Methods</i>: Norwegian residents ≥ 16 years of age who were admitted with a severe TBI to the country’s 4 major trauma centres in 2009 and 2010 were included, as were adults (16– 64 years) and elderly ...
    • Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study 

      Huijben, Jilske A.; Volovici, Victor; Cnossen, Maryse C.; Haitsma, Iain K.; Stocchetti, Nino; Maas, Andrew I. R.; Menon, David K.; Ercole, Ari; Citerio, Giuseppe; Nelson, David; Polinder, Suzanne; Steyerberg, Ewout W.; Lingsma, Hester F.; van der Jagt, Mathieu; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-13)
      <p><i>Background</i>: General supportive and preventive measures in the intensive care management of traumatic brain injury (TBI) aim to prevent or limit secondary brain injury and optimize recovery. The aim of this survey was to assess and quantify variation in perceptions on intensive care unit (ICU) management of patients with TBI in European neurotrauma centers.</p> <p><i>Methods</i>: We ...
    • Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study 

      Van Essen, Thomas; den Boogert, HF; Cnossen, MC; De Ruiter, Godard CW; Haitsma, Ian; Polinder, S; Steyerberg, Ewout W.; Menon, David; Maas, Andrew I. R.; Lingsma, Hester F; Peul, Wilco; Andelic, Nada; Helseth, Eirik; Roise, O; Røe, Cecilie; Vik, Anne; Skandsen, Toril; Anke, Audny; Frisvold, Shirin Kordasti (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-19)
      <p><i>Background</i>: Neurosurgical management of traumatic brain injury (TBI) is challenging, with only low-quality evidence. We aimed to explore differences in neurosurgical strategies for TBI across Europe.</p> <p><i>Methods</i>: A survey was sent to 68 centers participating in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. The ...
    • Variation in the practice of tracheal intubation in Europe after traumatic brain injury: a prospective cohort study 

      Gravesteijn, BY; Sewalt, C.; Ercole, Ari; Lecky, Fiona; Menon, David; Steyerberg, Ewout W; Maas, AIR; Lingsma, Hester F; Klimek, Magdalena; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røise, Olav; Røe, Cecilie; Schirmer-Mikalsen, Kari; Sandrød, Oddrun; Borgen Lund, Stine (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-13)
      Traumatic brain injury patients frequently undergo tracheal intubation. We aimed to assess current intubation practice in Europe and identify variation in practice. We analysed data from patients with traumatic brain injury included in the prospective cohort study collaborative European neurotrauma effectiveness research in traumatic brain injury (CENTER‐TBI) in 45 centres in 16 European countries. ...